Base-Position Error Rate Analysis of Next-Generation Sequencing Applied to Circulating Tumor DNA in Non-Small Cell Lung Cancer: A Prospective Study

BACKGROUND: Circulating tumor DNA (ctDNA) is an approved noninvasive biomarker to test for the presence of EGFR mutations at diagnosis or recurrence of lung cancer. However, studies evaluating ctDNA as a noninvasive “real-time” biomarker to provide prognostic and predictive information in treatment...

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Detalhes bibliográficos
Publicado no:PLoS Med
Main Authors: Pécuchet, Nicolas, Zonta, Eleonora, Didelot, Audrey, Combe, Pierre, Thibault, Constance, Gibault, Laure, Lours, Camille, Rozenholc, Yves, Taly, Valérie, Laurent-Puig, Pierre, Blons, Hélène, Fabre, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189949/
https://ncbi.nlm.nih.gov/pubmed/28027313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002199
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