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Single Molecule–Based fliFISH Validates Radial and Heterogeneous Gene Expression Patterns in Pancreatic Islet β-Cells

Single-cell RNA-sequencing (scRNA-Seq) technologies have greatly enhanced our understanding of islet cell transcriptomes and have revealed the existence of β-cell heterogeneity. However, comparison of scRNA-Seq data sets from different groups have highlighted inconsistencies in gene expression patte...

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Vydáno v:Diabetes
Hlavní autoři: Li, Fangjia, Hu, Dehong, Dieter, Cailin, Ansong, Charles, Sussel, Lori, Orr, Galya
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173798/
https://ncbi.nlm.nih.gov/pubmed/33685924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0802
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