The Sulfation Code of Tauopathies: Heparan Sulfate Proteoglycans in the Prion Like Spread of Tau Pathology

Tauopathies are a heterogenous family of progressive neurodegenerative diseases defined by the appearance of proteinaceous lesions within the brain composed of abnormally folded species of Microtubule Associated Protein Tau (tau). Alzheimer’s Disease (AD), the most common tauopathy, is the leading c...

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Bibliographic Details
Published in:Front Mol Biosci
Main Authors: Mah, Dylan, Zhao, Jing, Liu, Xinyue, Zhang, Fuming, Liu, Jian, Wang, Lianchun, Linhardt, Robert, Wang, Chunyu
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Molecular Biosciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173255/
https://ncbi.nlm.nih.gov/pubmed/34095227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.671458
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