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A Novel UPLC-MS/MS Assay for the Measurement of Linezolid and its Metabolite PNU-142300 in Human Serum and its Application to Patients With Renal Insufficiency

The contribution of the metabolites of linezolid to the associated myelosuppression is unknown in patients who are renal impairment. In this research, the purpose of our experiment was to explore and develop a quick and robust ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Wang, Yingying, Gu, Er-min, Du, Xiaoxiang, Xu, Ren-ai, Lin, Guanyang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173121/
https://ncbi.nlm.nih.gov/pubmed/34093181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.641872
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