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The prevalence, genetic complexity and population-specific founder effects of human autosomal recessive disorders

Autosomal recessive (AR) disorders pose a significant burden for public health. However, despite their clinical importance, epidemiology and molecular genetics of many AR diseases remain poorly characterized. Here, we analyzed the genetic variability of 508 genes associated with AR disorders based o...

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Detalhes bibliográficos
Publicado no:NPJ Genom Med
Main Authors: Xiao, Qingyang, Lauschke, Volker M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172936/
https://ncbi.nlm.nih.gov/pubmed/34078906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-021-00203-x
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