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The prevalence, genetic complexity and population-specific founder effects of human autosomal recessive disorders

Autosomal recessive (AR) disorders pose a significant burden for public health. However, despite their clinical importance, epidemiology and molecular genetics of many AR diseases remain poorly characterized. Here, we analyzed the genetic variability of 508 genes associated with AR disorders based o...

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Bibliographische Detailangaben
Veröffentlicht in:NPJ Genom Med
Hauptverfasser: Xiao, Qingyang, Lauschke, Volker M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172936/
https://ncbi.nlm.nih.gov/pubmed/34078906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-021-00203-x
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