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An evaluation of the self-assembly enhancing properties of cell-derived hexameric amyloid-β
A key hallmark of Alzheimer’s disease is the extracellular deposition of amyloid plaques composed primarily of the amyloidogenic amyloid-β (Aβ) peptide. The Aβ peptide is a product of sequential cleavage of the Amyloid Precursor Protein, the first step of which gives rise to a C-terminal Fragment (C...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8172837/ https://ncbi.nlm.nih.gov/pubmed/34078941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90680-y |
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