A methionine-Mettl3-N(6)-methyladenosine axis promotes polycystic kidney disease

Autosomal Dominant Polycystic kidney disease (ADPKD) is a common monogenic disorder marked by numerous progressively enlarging kidney cysts. Mettl3, a methyltransferase that catalyzes the abundant N(6)-methyladenosine (m(6)A) RNA modification, is implicated in development, but its role in most disea...

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Bibliografske podrobnosti
izdano v:Cell Metab
Main Authors: Ramalingam, Harini, Kashyap, Sonu, Cobo-Stark, Patricia, Flaten, Andrea, Chang, Chun-Mien, Hajarnis, Sachin, Hein, Kyaw Zaw, Lika, Jorgo, Warner, Gina M, Espindola-Netto, Jair M., Kumar, Ashwani, Kanchwala, Mohammed, Xing, Chao, Chini, Eduardo N., Patel, Vishal
Format: Artigo
Jezik:Inglês
Izdano: 2021
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172529/
https://ncbi.nlm.nih.gov/pubmed/33852874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2021.03.024
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