Chromatin accessibility identifies regulatory elements predictive of gene expression and disease outcome in multiple myeloma

PURPOSE: Multiple myeloma is a malignancy of plasma cells. Extensive genetic and transcriptional characterization of myeloma has identified subtypes with prognostic and therapeutic implications. In contrast, relatively little is known about the myeloma epigenome. EXPERIMENTAL DESIGN: CD138+CD38+ mye...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Barwick, Benjamin G., Gupta, Vikas A., Matulis, Shannon M., Patton, Jonathan C., Powell, Doris R., Gu, Yanyan, Jaye, David L., Conneely, Karen N., Lin, Yin C., Hofmeister, Craig C., Nooka, Ajay K., Keats, Jonathan J., Lonial, Sagar, Vertino, Paula M., Boise, Lawrence H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172525/
https://ncbi.nlm.nih.gov/pubmed/33731366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-2931
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