Detection of Mycobacterium tuberculosis complex DNA in CD34-positive peripheral blood mononuclear cells of asymptomatic tuberculosis contacts: an observational study

BACKGROUND: Haematopoietic stem cells expressing the CD34 surface marker have been posited as a niche for Mycobacterium tuberculosis complex bacilli during latent tuberculosis infection. Our aim was to determine whether M tuberculosis complex DNA is detectable in CD34-positive peripheral blood monon...

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Publicat a:Lancet Microbe
Autors principals: Belay, Mulugeta, Tulu, Begna, Younis, Sidra, Jolliffe, David A, Tayachew, Dawit, Manwandu, Hana, Abozen, Tenagnework, Tirfie, Emawayish A, Tegegn, Metasebia, Zewude, Aboma, Forrest, Sally, Mayito, Jonathan, Huggett, Jim F, Jones, Gerwyn M, O'Sullivan, Denise M, Martineau, Henny M, Noursadeghi, Mahdad, Chandran, Aneesh, Harris, Kathryn A, Nikolayevskyy, Vlad, Demaret, Julie, Berg, Stefan, Vordermeier, Martin, Balcha, Taye T, Aseffa, Abraham, Ameni, Gobena, Abebe, Markos, Reece, Stephen T, Martineau, Adrian R
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Ltd 2021
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172384/
https://ncbi.nlm.nih.gov/pubmed/34100007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2666-5247(21)00043-4
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