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Detection of Mycobacterium tuberculosis complex DNA in CD34-positive peripheral blood mononuclear cells of asymptomatic tuberculosis contacts: an observational study

BACKGROUND: Haematopoietic stem cells expressing the CD34 surface marker have been posited as a niche for Mycobacterium tuberculosis complex bacilli during latent tuberculosis infection. Our aim was to determine whether M tuberculosis complex DNA is detectable in CD34-positive peripheral blood monon...

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Bibliografiske detaljer
Udgivet i:Lancet Microbe
Main Authors: Belay, Mulugeta, Tulu, Begna, Younis, Sidra, Jolliffe, David A, Tayachew, Dawit, Manwandu, Hana, Abozen, Tenagnework, Tirfie, Emawayish A, Tegegn, Metasebia, Zewude, Aboma, Forrest, Sally, Mayito, Jonathan, Huggett, Jim F, Jones, Gerwyn M, O'Sullivan, Denise M, Martineau, Henny M, Noursadeghi, Mahdad, Chandran, Aneesh, Harris, Kathryn A, Nikolayevskyy, Vlad, Demaret, Julie, Berg, Stefan, Vordermeier, Martin, Balcha, Taye T, Aseffa, Abraham, Ameni, Gobena, Abebe, Markos, Reece, Stephen T, Martineau, Adrian R
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Ltd 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172384/
https://ncbi.nlm.nih.gov/pubmed/34100007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2666-5247(21)00043-4
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