Dysbiosis-induced Secondary Bile Acid Deficiency Promotes Intestinal Inflammation

Secondary bile acids (SBAs) are derived from primary bile acids (PBAs) in a process reliant on biosynthetic capabilities possessed by few microbes. To evaluate the role of BAs in intestinal inflammation, we performed metabolomic, microbiome, metagenomic, and transcriptomic profiling of stool from il...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Sinha, Sidhartha R., Haileselassie, Yeneneh, Nguyen, Linh P., Tropini, Carolina, Wang, Min, Becker, Laren S., Sim, Davis, Jarr, Karolin, Spear, Estelle T., Singh, Gulshan, Namkoong, Hong, Bittinger, Kyle, Fischbach, Michael A., Sonnenburg, Justin L., Habtezion, Aida
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172352/
https://ncbi.nlm.nih.gov/pubmed/32101703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.01.021
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