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Age-dependent Shift in Macrophage Polarization Causes Inflammation Mediated Degeneration of Enteric Nervous System

OBJECTIVE: The enteric nervous system (ENS) undergoes neuronal loss and degenerative changes with age. The cause of this neurodegeneration is poorly understood. Muscularis macrophages (MMs) residing in close proximity to enteric ganglia maintain neuromuscular function via direct crosstalk with enter...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Becker, Laren, Nguyen, Linh, Gill, Jaspreet, Kulkarni, Subhash, Pasricha, Pankaj Jay, Habtezion, Aida
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565713/
https://ncbi.nlm.nih.gov/pubmed/28228489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-312940
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