Synthesis and (15)N NMR Signal Amplification by Reversible Exchange of [(15)N]Dalfampridine at Microtesla Magnetic Fields

Signal Amplification by Reversible Exchange (SABRE) technique enables nuclear spin hyperpolarization of wide range of compounds using parahydrogen. Here we present the synthetic approach to prepare (15)N-labeled [(15)N]dalfampridine (4-amino[(15)N]pyridine) utilized as a drug to reduce the symptoms...

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Publicat a:Chemphyschem
Autors principals: Chukanov, Nikita V., Salnikov, Oleg G., Trofimov, Ivan A., Kabir, Mohammad S. H., Kovtunov, Kirill V., Koptyug, Igor V., Chekmenev, Eduard Y.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172086/
https://ncbi.nlm.nih.gov/pubmed/33738893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cphc.202100109
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