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Synthesis and (15)N NMR Signal Amplification by Reversible Exchange of [(15)N]Dalfampridine at Microtesla Magnetic Fields

Signal Amplification by Reversible Exchange (SABRE) technique enables nuclear spin hyperpolarization of wide range of compounds using parahydrogen. Here we present the synthetic approach to prepare (15)N-labeled [(15)N]dalfampridine (4-amino[(15)N]pyridine) utilized as a drug to reduce the symptoms...

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Detalhes bibliográficos
Publicado no:Chemphyschem
Main Authors: Chukanov, Nikita V., Salnikov, Oleg G., Trofimov, Ivan A., Kabir, Mohammad S. H., Kovtunov, Kirill V., Koptyug, Igor V., Chekmenev, Eduard Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172086/
https://ncbi.nlm.nih.gov/pubmed/33738893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cphc.202100109
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