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Covalent and non-covalent albumin binding of Au(i) bis-NHCs via post-synthetic amide modification
Recent decades have witnessed the emergence of Au(i) bis-N-heterocyclic carbenes (NHCs) as potential anticancer agents. However, these systems exhibit little interaction with serum proteins (e.g., human serum albumin), which presumably impacts their pharmacokinetic profile and tumor exposure. Antica...
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| Vydáno v: | Chem Sci |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Royal Society of Chemistry
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8171490/ https://ncbi.nlm.nih.gov/pubmed/34163845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1sc01055g |
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