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Anticancer gold(iii)-bisphosphine complex alters the mitochondrial electron transport chain to induce in vivo tumor inhibition

Expanding the chemical diversity of metal complexes provides a robust platform to generate functional bioactive reagents. To access an excellent repository of metal-based compounds for probe/drug discovery, we capitalized on the rich chemistry of gold to create organometallic gold(iii) compounds by...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Kim, Jong Hyun, Ofori, Samuel, Parkin, Sean, Vekaria, Hemendra, Sullivan, Patrick G., Awuah, Samuel G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8171344/
https://ncbi.nlm.nih.gov/pubmed/34163837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1sc01418h
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