Effective DNA damage response after acute but not chronic immune challenge: SARS-CoV-2 vaccine versus Systemic Lupus Erythematosus

Whether and how an acute immune challenge may affect DNA Damage Response (DDR) is unknown. By studying vaccinations against Influenza and SARS-CoV-2 (mRNA-based) we found acute increases of type-I interferon-inducible gene expression, oxidative stress and DNA damage accumulation in blood mononuclear...

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Detalhes bibliográficos
Publicado no:Clin Immunol
Main Authors: Ntouros, Panagiotis A., Vlachogiannis, Nikolaos I., Pappa, Maria, Nezos, Adrianos, Mavragani, Clio P., Tektonidou, Maria G., Souliotis, Vassilis L., Sfikakis, Petros P.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2021
Assuntos:
Full Length Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8171000/
https://ncbi.nlm.nih.gov/pubmed/34089859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2021.108765
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