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Less airway inflammation and goblet cell metaplasia in an IL-33-induced asthma model of leptin-deficient obese mice
BACKGROUND: Obesity-associated asthma is a phenotype of severe asthma. Late-onset, non-eosinophilic and female-dominant phenotype is highly symptomatic and difficult to treat. Leptin, an adipokine, exerts an immunomodulatory effect. IL-33 associated with innate immunity induces type 2 inflammation a...
Gorde:
| Argitaratua izan da: | Respir Res |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
BioMed Central
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8170793/ https://ncbi.nlm.nih.gov/pubmed/34074279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01763-3 |
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