Palmitoylated antigens for the induction of anti-tumor CD8(+) T cells and enhanced tumor recognition

Induction of tumor-specific cytotoxic CD8(+) T cells (CTLs) via immunization relies on the presentation of tumor-associated peptides in major histocompatibility complex (MHC) class I molecules by dendritic cells (DCs). To achieve presentation of exogenous peptides into MHC class I, cytosolic process...

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Publicado en:Mol Ther Oncolytics
Autores principales: Stolk, Dorian A., Horrevorts, Sophie K., Schetters, Sjoerd T.T., Kruijssen, Laura J.W., Duinkerken, Sanne, Keuning, Eelco, Ambrosini, Martino, Kalay, Hakan, van de Ven, Rieneke, Garcia-Vallejo, Juan J., de Gruijl, Tanja D., van Vliet, Sandra J., van Kooyk, Yvette
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8170356/
https://ncbi.nlm.nih.gov/pubmed/34141869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2021.04.009
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