Lipo-Based Vaccines as an Approach to Target Dendritic Cells for Induction of T- and iNKT Cell Responses

In this study we developed a liposome-based vaccine containing palmitoylated synthetic long peptides (SLP) and alpha galactosylceramide (αGC) to specifically target dendritic cells (DC) for activation of both innate (invariant natural killer T-cells [iNKT]) and adaptive (CD8(+) T-cells) players of t...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Stolk, Dorian A., de Haas, Aram, Vree, Jana, Duinkerken, Sanne, Lübbers, Joyce, van de Ven, Rieneke, Ambrosini, Martino, Kalay, Hakan, Bruijns, Sven, van der Vliet, Hans J., de Gruijl, Tanja D., van Kooyk, Yvette
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7267035/
https://ncbi.nlm.nih.gov/pubmed/32536918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00990
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