Lipo-Based Vaccines as an Approach to Target Dendritic Cells for Induction of T- and iNKT Cell Responses

In this study we developed a liposome-based vaccine containing palmitoylated synthetic long peptides (SLP) and alpha galactosylceramide (αGC) to specifically target dendritic cells (DC) for activation of both innate (invariant natural killer T-cells [iNKT]) and adaptive (CD8(+) T-cells) players of t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Stolk, Dorian A., de Haas, Aram, Vree, Jana, Duinkerken, Sanne, Lübbers, Joyce, van de Ven, Rieneke, Ambrosini, Martino, Kalay, Hakan, Bruijns, Sven, van der Vliet, Hans J., de Gruijl, Tanja D., van Kooyk, Yvette
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7267035/
https://ncbi.nlm.nih.gov/pubmed/32536918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00990
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