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FUT8-AS1 Inhibits the Malignancy of Melanoma Through Promoting miR-145-5p Biogenesis and Suppressing NRAS/MAPK Signaling

Melanoma is the major lethal skin malignancy. However, the critical molecular drivers governing melanoma progression and prognosis are still not clear. By analyzing The Cancer Genome Atlas (TCGA) data, we identified FUT8-AS1 as a prognosis-related long non-coding RNA (lncRNA) in melanoma. We further...

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Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Chen, Xiang-jun, Liu, Sha, Han, Dong-mei, Han, De-zhi, Sun, Wei-jing, Zhao, Xiao-chun, Liang, Jun-qing, Yu, Li
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8170315/
https://ncbi.nlm.nih.gov/pubmed/34094894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.586085
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