Endoplasmic reticulum stress promotes epithelial-mesenchymal transition via the PERK signaling pathway in paraquat-induced pulmonary fibrosis

Pulmonary fibrosis is the primary reason for mortality in patients with paraquat (PQ) poisoning. Our previous study demonstrated that epithelial-mesenchymal transition (EMT) had a role in PQ-induced pulmonary fibrosis. However, the role of endoplasmic reticulum (ER) stress in PQ-induced EMT remains...

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Veröffentlicht in:Mol Med Rep
Hauptverfasser: Meng, Xiaoxiao, Liu, Kan, Xie, Hui, Zhu, Yong, Jin, Wei, Lu, Jian, Wang, Ruilan
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2021
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8170262/
https://ncbi.nlm.nih.gov/pubmed/34036384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12164
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