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Hypoxia-inducible factor-1α regulates epithelial-to-mesenchymal transition in paraquat-induced pulmonary fibrosis by activating lysyl oxidase

Pulmonary fibrosis (PF) is one of the most prevalent causes of death following paraquat (PQ) poisoning. As demonstrated in previous studies by the present authors, epithelial-to-mesenchymal transition (EMT) is associated with PQ-induced PF. In addition, hypoxia-inducible factor-1α (HIF-1α) and lysyl...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Lu, Jian, Qian, Yongbing, Jin, Wei, Tian, Rui, Zhu, Yong, Wang, Jinfeng, Meng, Xiaoxiao, Wang, Ruilan
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792814/
https://ncbi.nlm.nih.gov/pubmed/29467842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5677
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