Cargando...

Copper-catalyzed carbo-difluoromethylation of alkenes via radical relay

Organic molecules that contain alkyl-difluoromethyl moieties have received increased attention in medicinal chemistry, but their synthesis in a modular and late-stage fashion remains challenging. We report herein an efficient copper-catalyzed radical relay approach for the carbo-difluoromethylation...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Cai, Aijie, Yan, Wenhao, Zeng, Xiaojun, Zacate, Samson B., Chao, Tzu-Hsuan, Krause, Jeanette A., Cheng, Mu-Jeng, Liu, Wei
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169770/
https://ncbi.nlm.nih.gov/pubmed/34075051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23590-2
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!