The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2

The 4F2 cell-surface antigen heavy chain (4F2hc) forms a heterodimeric complex with L-type amino acid transporter 1 (LAT1) and transports large neutral essential amino acids. However, in contrast to the traditional role of LAT1 in various cancers, the role of 4F2hc has largely remained unknown. The...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Maimaiti, Maihulan, Sakamoto, Shinichi, Sugiura, Masahiro, Kanesaka, Manato, Fujimoto, Ayumi, Matsusaka, Keisuke, Xu, Minhui, Ando, Keisuke, Saito, Shinpei, Wakai, Ken, Imamura, Yusuke, Nakayama, Keiichi, Kanai, Yoshikatsu, Kaneda, Atsushi, Ikehara, Yuzuru, Ikeda, Jun-Ichiro, Anzai, Naohiko, Ichikawa, Tomohiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169706/
https://ncbi.nlm.nih.gov/pubmed/34075107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90748-9
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