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Bacterial efflux transporters’ polyspecificity - a gift and a curse?

All mechanisms of clinical antibiotic resistance benefit from activities of polyspecific efflux pumps acting to reduce intracellular accumulation of toxins and antibiotics. In Gram-negative bacteria, the major polyspecific efflux transporters belong to the Resistance-Nodulation-cell Division (RND) s...

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Detalhes bibliográficos
Publicado no:Curr Opin Microbiol
Main Authors: Zgurskaya, Helen I., Malloci, Giuliano, Chandar, Brinda, Vargiu, Attilio, Ruggerone, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169617/
https://ncbi.nlm.nih.gov/pubmed/33940284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2021.03.009
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