Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation

Smoothened is a key receptor of the hedgehog pathway, but the roles of Smoothened in cardiac development remain incompletely understood. In this study, we found that the conditional knockout of Smoothened from the mesoderm impaired the development of the venous pole of the heart and resulted in hypo...

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Detalhes bibliográficos
Publicado no:Open Biol
Principais autores: Zhang, Chaohui, Li, Yuxin, Cao, Jiaheng, Yu, Beibei, Zhang, Kaiyue, Li, Ke, Xu, Xinhui, Guo, Zhikun, Liang, Yinming, Yang, Xiao, Yang, Zhongzhou, Sun, Yunfu, Kaartinen, Vesa, Ding, Keyue, Wang, Jikui
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169207/
https://ncbi.nlm.nih.gov/pubmed/34062094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.210020
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