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Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation
Smoothened is a key receptor of the hedgehog pathway, but the roles of Smoothened in cardiac development remain incompletely understood. In this study, we found that the conditional knockout of Smoothened from the mesoderm impaired the development of the venous pole of the heart and resulted in hypo...
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| 發表在: | Open Biol |
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| Main Authors: | , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Royal Society
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8169207/ https://ncbi.nlm.nih.gov/pubmed/34062094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.210020 |
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