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Cholesterol Contributes to Male Sex Differentiation Through Its Developmental Role in Androgen Synthesis and Hedgehog Signaling

Two specialized functions of cholesterol during fetal development include serving as a precursor to androgen synthesis and supporting hedgehog (HH) signaling activity. Androgens are produced by the testes to facilitate masculinization of the fetus. Recent evidence shows that intricate interactions b...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Endocrinology
Main Authors: Kothandapani, Anbarasi, Jefcoate, Colin R, Jorgensen, Joan S
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168945/
https://ncbi.nlm.nih.gov/pubmed/33784378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqab066
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