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MarH, a Bifunctional Enzyme Involved in the Condensation and Hydroxylation Steps of the Marineosin Biosynthetic Pathway

A novel bifunctional enzyme, MarH has been identified and its key functional role in the marineosin biosynthesis successfully probed. MarH catalyzes 1) a condensation step between 4-methoxy-2,2ʹ-bipyrrole-5-carboxaldehyde (MBC) and 2-undecylpyrrole (UP) to form undecylprodiginine (UPG), and 2) hydro...

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Detalhes bibliográficos
Publicado no:Org Lett
Principais autores: Lu, Wanli, Kancharla, Papireddy, Reynolds, Kevin A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168799/
https://ncbi.nlm.nih.gov/pubmed/28271893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b00093
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