Protective effects of carbonic anhydrase inhibition in brain ischaemia in vitro and in vivo models

Ischaemic stroke is a leading cause of death and disability. One of the major pathogenic mechanisms after ischaemia includes the switch to the glycolytic pathway, leading to tissue acidification. Carbonic anhydrase (CA) contributes to pH regulation. A new generation of CA inhibitors, AN11-740 and AN...

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Dades bibliogràfiques
Publicat a:J Enzyme Inhib Med Chem
Autors principals: Dettori, Ilaria, Fusco, Irene, Bulli, Irene, Gaviano, Lisa, Coppi, Elisabetta, Cherchi, Federica, Venturini, Martina, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Nocentini, Alessio, Supuran, Claudiu T., Pugliese, Anna Maria, Pedata, Felicita
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2021
Matèries:
Short Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168743/
https://ncbi.nlm.nih.gov/pubmed/34056989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1907575
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