CTCF looping is established during gastrulation in medaka embryos

Chromatin looping plays an important role in genome regulation. However, because ChIP-seq and loop-resolution Hi-C (DNA-DNA proximity ligation) are extremely challenging in mammalian early embryos, the developmental stage at which cohesin-mediated loops form remains unknown. Here, we study early dev...

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Veröffentlicht in:Genome Res
Hauptverfasser: Nakamura, Ryohei, Motai, Yuichi, Kumagai, Masahiko, Wike, Candice L., Nishiyama, Haruyo, Nakatani, Yoichiro, Durand, Neva C., Kondo, Kaori, Kondo, Takashi, Tsukahara, Tatsuya, Shimada, Atsuko, Cairns, Bradley R., Aiden, Erez Lieberman, Morishita, Shinichi, Takeda, Hiroyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168583/
https://ncbi.nlm.nih.gov/pubmed/34006570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.269951.120
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