Natural antisense transcript of Period2, Per2AS, regulates the amplitude of the mouse circadian clock

In mammals, a set of core clock genes form transcription–translation feedback loops to generate circadian oscillations. We and others recently identified a novel transcript at the Period2 (Per2) locus that is transcribed from the antisense strand of Per2. This transcript, Per2AS, is expressed rhythm...

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Pubblicato in:Genes Dev
Autori principali: Mosig, Rebecca A., Castaneda, Allison N., Deslauriers, Jacob C., Frazier, Landon P., He, Kevin L., Maghzian, Naseem, Pokharel, Aarati, Schrier, Camille T., Zhu, Lily, Koike, Nobuya, Tyson, John J., Green, Carla B., Takahashi, Joseph S., Kojima, Shihoko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2021
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168560/
https://ncbi.nlm.nih.gov/pubmed/34016691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.343541.120
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