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Natural antisense transcript of Period2, Per2AS, regulates the amplitude of the mouse circadian clock

In mammals, a set of core clock genes form transcription–translation feedback loops to generate circadian oscillations. We and others recently identified a novel transcript at the Period2 (Per2) locus that is transcribed from the antisense strand of Per2. This transcript, Per2AS, is expressed rhythm...

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Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Mosig, Rebecca A., Castaneda, Allison N., Deslauriers, Jacob C., Frazier, Landon P., He, Kevin L., Maghzian, Naseem, Pokharel, Aarati, Schrier, Camille T., Zhu, Lily, Koike, Nobuya, Tyson, John J., Green, Carla B., Takahashi, Joseph S., Kojima, Shihoko
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168560/
https://ncbi.nlm.nih.gov/pubmed/34016691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.343541.120
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