Prognostic significance of translocations in the presence of mutated IGHV and of cytogenetic complexity at diagnosis of chronic lymphocytic leukemia

Mutations of the IGH variable region in patients with chronic lymphocytic leukemia are associated with a favorable prognosis, whereas cytogenetic complexity (≥3 unrelated aberrations) and translocations have been associated with an unfavorable prognosis. While mutational status of IGHV is stable, cy...

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書誌詳細
出版年:Haematologica
主要な著者: Heerema, Nyla A., Muthusamy, Natarajan, Zhao, Qiuhong, Ruppert, Amy S., Breidenbach, Heather, Andritsos, Leslie A., Grever, Michael R., Maddocks, Kami J., Woyach, Jennifer, Awan, Farrukh, Long, Meixiao, Gordon, Amber, Coombes, Caitlin, Byrd, John C.
フォーマット: Artigo
言語:Inglês
出版事項: Fondazione Ferrata Storti 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168513/
https://ncbi.nlm.nih.gov/pubmed/32414849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.212571
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