Canonical Secretomes, Innate Immune Caspase-1-, 4/11-Gasdermin D Non-Canonical Secretomes and Exosomes May Contribute to Maintain Treg-Ness for Treg Immunosuppression, Tissue Repair and Modulate Anti-Tumor Immunity via ROS Pathways

We performed a transcriptomic analyses using the strategies we pioneered and made the following findings: 1) Normal lymphoid Tregs, diseased kidney Tregs, splenic Tregs from mice with injured muscle have 3, 17 and 3 specific (S-) pathways, respectively; 2) Tumor splenic Tregs share 12 pathways with...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Ni, Dong, Tang, TingTing, Lu, Yifan, Xu, Keman, Shao, Ying, Saaoud, Fatma, Saredy, Jason, Liu, Lu, Drummer, Charles, Sun, Yu, Hu, Wenhui, Lopez-Pastrana, Jahaira, Luo, Jin J., Jiang, Xiaohua, Choi, Eric T., Wang, Hong, Yang, Xiaofeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168470/
https://ncbi.nlm.nih.gov/pubmed/34084175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.678201
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