Endothelial Immunity Trained by Coronavirus Infections, DAMP Stimulations and Regulated by Anti-Oxidant NRF2 May Contribute to Inflammations, Myelopoiesis, COVID-19 Cytokine Storms and Thromboembolism

To characterize transcriptomic changes in endothelial cells (ECs) infected by coronaviruses, and stimulated by DAMPs, the expressions of 1311 innate immune regulatomic genes (IGs) were examined in 28 EC microarray datasets with 7 monocyte datasets as controls. We made the following findings: The maj...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Shao, Ying, Saredy, Jason, Xu, Keman, Sun, Yu, Saaoud, Fatma, Drummer, Charles, Lu, Yifan, Luo, Jin J., Lopez-Pastrana, Jahaira, Choi, Eric T., Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8269631/
https://ncbi.nlm.nih.gov/pubmed/34248940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.653110
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