Endothelial Immunity Trained by Coronavirus Infections, DAMP Stimulations and Regulated by Anti-Oxidant NRF2 May Contribute to Inflammations, Myelopoiesis, COVID-19 Cytokine Storms and Thromboembolism

To characterize transcriptomic changes in endothelial cells (ECs) infected by coronaviruses, and stimulated by DAMPs, the expressions of 1311 innate immune regulatomic genes (IGs) were examined in 28 EC microarray datasets with 7 monocyte datasets as controls. We made the following findings: The maj...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Shao, Ying, Saredy, Jason, Xu, Keman, Sun, Yu, Saaoud, Fatma, Drummer, Charles, Lu, Yifan, Luo, Jin J., Lopez-Pastrana, Jahaira, Choi, Eric T., Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8269631/
https://ncbi.nlm.nih.gov/pubmed/34248940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.653110
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