Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research.

Currently nitazoxanide is being assessed as a candidate therapeutic for SARS-CoV-2. Unlike many other candidates being investigated, tizoxanide (the active metabolite of nitazoxanide) plasma concentrations achieve antiviral levels after administration of the approved dose, although higher doses are...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Neary, Megan, Arshad, Usman, Tatham, Lee, Pertinez, Henry, Box, Helen, Rajoli, Rajith KR, Valentijn, Anthony, Sharp, Joanne, Rannard, Steve P, Biagini, Giancarlo A, Curley, Paul, Owen, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168394/
https://ncbi.nlm.nih.gov/pubmed/34075381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.05.27.445500
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