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Single-Molecule Dynamics of SARS-CoV-2 5’ Cap Recognition by Human eIF4F
Coronaviruses initiate translation through recognition of the viral RNA 5’ m (7) GpppA (m) cap by translation factor eIF4F. eIF4F is a heterotrimeric protein complex with cap-binding, RNA-binding, and RNA helicase activities. Modulating eIF4F function through cellular regulation or small-molecule in...
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| Publicado no: | bioRxiv |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8168387/ https://ncbi.nlm.nih.gov/pubmed/34075378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.05.26.445185 |
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