HGG-21. MALIGNANT SYNAPTIC PLASTICITY IN PEDIATRIC HIGH-GRADE GLIOMAS

Pediatric high-grade gliomas (pHGG) are a devastating group of diseases that urgently require novel therapeutic options. We have previously demonstrated that pHGGs directly synapse onto neurons and the subsequent tumor cell depolarization, mediated by calcium-permeable AMPA channels, promotes their...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Taylor, Kathryn, Barron, Tara, Hartmann, Griffin, Zhang, Helena, Hui, Alexa, Gillespie, Shawn, Monje, Michelle
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2021
Assuntos:
High Grade Gliomas
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168239/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.085
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