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BIOL-10. DISTRIBUTION AND VULNERABILITY OF TRANSCRIPTIONAL OUTPUTS ACROSS THE GENOME IN MYC-AMPLIFIED MEDULLOBLASTOMA CELLS

Myc plays a central role in tumorigenesis by orchestrating the expression of genes essential to numerous cellular processes. While it is well established that Myc functions by binding to its target genes to regulate their transcription, the distribution of the transcriptional output across human gen...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Yang, Rui, Wang, Wenzhe, Dong, Meichen, Roso, Kristen, Bao, Xuhui, Pirozzi, Christopher, Bigner, Darell, Yan, Hai, Ashley, David, Zhabotynsky, Vasyl, Zou, Fei, He, Yiping
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168194/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.017
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