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βKlotho, a direct target of miR-206, contributes to the growth of hepatoblastoma through augmenting PI3K/Akt/mTOR signaling

Hepatoblastoma (HB) is the most frequent pediatric liver malignancy. However, the treatment outcome for patients with advanced-stage HB remains unsatisfactory. Accumulating evidence indicates that βKlotho (KLB) acts as an oncogene or a tumor-suppressor gene in a context-dependent manner. Despite thi...

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Pubblicato in:Am J Cancer Res
Autori principali: Chen, Tong, Chen, Jianglong, Zhao, Xiuhao, Zhou, Jing, Sheng, Qingfeng, Zhu, Linlin, Lv, Zhibao
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167675/
https://ncbi.nlm.nih.gov/pubmed/34094665
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