Combining Mass Spectrometry-Based Phosphoproteomics with a Network-Based Approach to Reveal FLT3-Dependent Mechanisms of Chemoresistance

FLT3 mutations are the most frequently identified genetic alterations in acute myeloid leukemia (AML) and are associated with poor clinical outcome, relapse and chemotherapeutic resistance. Elucidating the molecular mechanisms underlying FLT3-dependent pathogenesis and drug resistance is a crucial g...

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Dades bibliogràfiques
Publicat a:Proteomes
Autors principals: Pugliese, Giusj Monia, Latini, Sara, Massacci, Giorgia, Perfetto, Livia, Sacco, Francesca
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167576/
https://ncbi.nlm.nih.gov/pubmed/33925552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/proteomes9020019
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