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Optic vesicle morphogenesis requires primary cilia

Arl13b is a gene known to regulate ciliogenesis. Functional alterations in this gene's activity have been associated with Joubert syndrome. We found that in Arl13 null mouse embryos the orientation of the optic cup is inverted, such that the lens is abnormally surrounded by an inverted optic cu...

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Publicat a:Dev Biol
Autors principals: Fiore, Luciano, Takata, Nozomu, Acosta, Sandra, Ma, Wanshu, Pandit, Tanushree, Oxendine, Michael, Oliver, Guillermo
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167498/
https://ncbi.nlm.nih.gov/pubmed/32169553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2020.02.016
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