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Optic vesicle morphogenesis requires primary cilia
Arl13b is a gene known to regulate ciliogenesis. Functional alterations in this gene's activity have been associated with Joubert syndrome. We found that in Arl13 null mouse embryos the orientation of the optic cup is inverted, such that the lens is abnormally surrounded by an inverted optic cu...
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| Veröffentlicht in: | Dev Biol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8167498/ https://ncbi.nlm.nih.gov/pubmed/32169553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2020.02.016 |
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