STAT3-BDNF-TrkB signaling promotes alveolar epithelial regeneration after lung injury

Alveolar epithelial regeneration is essential for recovery from devastating lung diseases. This process occurs when type II alveolar pneumocytes (AT2) proliferate and transdifferentiate into type I alveolar pneumocytes (AT1). We used genome-wide analysis of chromatin accessibility and gene expressio...

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Udgivet i:Nat Cell Biol
Main Authors: Paris, Andrew J., Hayer, Katharina E., Oved, Joseph H., Avgousti, Daphne C., Toulmin, Sushila A., Zepp, Jarod A., Zacharias, William J., Katzen, Jeremy B., Basil, Maria C., Kremp, Madison M., Slamowitz, April R., Jayachandran, Sowmya, Sivakumar, Aravind, Dai, Ning, Wang, Ping, Frank, David B., Eisenlohr, Laurence C., Cantu, Edward, Beers, Michael F., Weitzman, Matthew D., Morrisey, Edward E., Worthen, G. Scott
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167437/
https://ncbi.nlm.nih.gov/pubmed/32989251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-0569-x
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