Distinct mesenchymal lineages and niches promote epithelial self-renewal and myofibrogenesis in the lung

The lung is an architecturally complex organ comprised of a heterogeneous mixture of various epithelial and mesenchymal lineages. We have used single-cell RNA-sequencing and signaling lineage reporters to generate a spatial and transcriptional map of the lung mesenchyme. We find that each mesenchyma...

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Bibliographic Details
Published in:Cell
Main Authors: Zepp, Jarod A., Zacharias, William J., Frank, David B., Cavanaugh, Christina A., Zhou, Su, Morley, Michael P., Morrisey, Edward E.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718193/
https://ncbi.nlm.nih.gov/pubmed/28886382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.034
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