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Distinct mesenchymal lineages and niches promote epithelial self-renewal and myofibrogenesis in the lung

The lung is an architecturally complex organ comprised of a heterogeneous mixture of various epithelial and mesenchymal lineages. We have used single-cell RNA-sequencing and signaling lineage reporters to generate a spatial and transcriptional map of the lung mesenchyme. We find that each mesenchyma...

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Podrobná bibliografie
Vydáno v:Cell
Hlavní autoři: Zepp, Jarod A., Zacharias, William J., Frank, David B., Cavanaugh, Christina A., Zhou, Su, Morley, Michael P., Morrisey, Edward E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718193/
https://ncbi.nlm.nih.gov/pubmed/28886382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.034
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