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Poly(U)‐specific endoribonuclease ENDOU promotes translation of human CHOP mRNA by releasing uORF element‐mediated inhibition
Upstream open reading frames (uORFs) are known to negatively affect translation of the downstream ORF. The regulatory proteins involved in relieving this inhibition are however poorly characterized. In response to cellular stress, eIF2α phosphorylation leads to an inhibition of global protein synthe...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8167367/ https://ncbi.nlm.nih.gov/pubmed/33511665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019104123 |
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