A single‐cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast

To examine global changes in breast heterogeneity across different states, we determined the single‐cell transcriptomes of > 340,000 cells encompassing normal breast, preneoplastic BRCA1 (+/–) tissue, the major breast cancer subtypes, and pairs of tumors and involved lymph nodes. Elucidation of t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO J
Egile Nagusiak: Pal, Bhupinder, Chen, Yunshun, Vaillant, François, Capaldo, Bianca D, Joyce, Rachel, Song, Xiaoyu, Bryant, Vanessa L, Penington, Jocelyn S, Di Stefano, Leon, Tubau Ribera, Nina, Wilcox, Stephen, Mann, Gregory B, Papenfuss, Anthony T, Lindeman, Geoffrey J, Smyth, Gordon K, Visvader, Jane E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2021
Gaiak:
Resource
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167363/
https://ncbi.nlm.nih.gov/pubmed/33950524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020107333
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