A single‐cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast

To examine global changes in breast heterogeneity across different states, we determined the single‐cell transcriptomes of > 340,000 cells encompassing normal breast, preneoplastic BRCA1 (+/–) tissue, the major breast cancer subtypes, and pairs of tumors and involved lymph nodes. Elucidation of t...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Pal, Bhupinder, Chen, Yunshun, Vaillant, François, Capaldo, Bianca D, Joyce, Rachel, Song, Xiaoyu, Bryant, Vanessa L, Penington, Jocelyn S, Di Stefano, Leon, Tubau Ribera, Nina, Wilcox, Stephen, Mann, Gregory B, Papenfuss, Anthony T, Lindeman, Geoffrey J, Smyth, Gordon K, Visvader, Jane E
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167363/
https://ncbi.nlm.nih.gov/pubmed/33950524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020107333
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